Interleukin-6 contributes to early fasting-induced free fatty acid mobilization

1 mice 2 3 Stephan Wueest, Flurin Item, Christina N. Boyle, Paulin Jirkof, Nikola Cesarovic, 4 Helga Ellingsgaard, Marianne Böni-Schnetzler, Katharina Timper, Margarete Arras, 5 Marc Y. Donath, Thomas A. Lutz , Eugen J. Schoenle, Daniel Konrad 6 7 Department of Pediatric Endocrinology and Diabetology and Children’s Research 8 Center, University Children's Hospital, Zurich, Switzerland 9 Institute of Veterinary Physiology, University of Zurich, Zurich, Switzerland 10 Division of Surgical Research, University Hospital Zurich, Zurich Switzerland 11 Division of Endocrinology, Diabetes & Metabolism and Department of Biomedicine, 12 University Hospital and University of Basel, Basel, Switzerland 13 ZurichCenter for Integrative Human Physiology, University of Zurich, Zurich, 14 Switzerland 15 Institute of Laboratory Animal Science, University of Zurich, Zurich, Switzerland 16 17 *S.W. and F.I. contributed equally to this study. 18 19 20 Running title: IL-6 mediated release of free fatty acids in early fasting 21 22 23 Articles in PresS. Am J Physiol Regul Integr Comp Physiol (April 2, 2014). doi:10.1152/ajpregu.00533.2013